HORDB

ID: hor000968
Uniprot ID: Q8JHB9
Protein name: Cholecystokinin-8
Gene name: CCK
Organism: Python molurus (Indian python)
Family: Gastrin/cholecystokinin family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Python (genus), Pythonidae (family), Henophidia (superfamily), Serpentes (infraorder), Toxicofera, Episquamata, Unidentata, Bifurcata, Squamata (order), Lepidosauria (class), Sauria, Sauropsida, Amniota, Tetrapoda, Dipnotetrapodomorpha, Sarcopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity; GO:0005184 neuropeptide hormone activity
GO BP: GO:0007165 signal transduction; GO:0007586 digestion; GO:0008217 regulation of blood pressure
GO CC: GO:0005576 extracellular region

Sequence: DYMGWMDF
Length: 8
Propeptide: MYSGICSCLFLAVLSSSSLGQQISGSQHANPAVTDLEQSLLENHRHTRIPTSGRPIQLVDGSIDQKANLGALLAKYLQQARRGSTGKASVMGLQNFDPTHRIKDRDYMGWMDFGRRSAEEYEYSS
Signal peptide: MYSGICSCLFLAVLSSSSLG
Modification: T2 Sulfotyrosine;T8 Phenylalanine amide
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor000968_AF2.pdb

hor000968_ESM.pdb

Mass:	118924	Formula:	C49H61N9O14S2
Absent amino acids:	ACEHIKLNPQRSTV	Common amino acids:	DM
pI:	3.49	Basic residues:	0
Polar residues:	2	Hydrophobic residues:	2
Hydrophobicity:	-37.5	Boman Index:	-663
Half-Life:	1.1 hour	Half-Life Yeast:	3 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	0
Instability Index:	9927.5	Extinction Coefficient cystines:	6990
Absorbance 280nm:	998.57